Calexico is a city in southern Imperial County, California. Situated on the Mexican border, it is linked economically with the much larger city of …Calexico is a city in southern Imperial County, California. Situated on the Mexican border, it is linked economically with the much larger city of Mexicali, the capital of the Mexican state of Baja California. It is about 122 miles east of San Diego and 62 miles west of Yuma, Arizona. Calexico, along with six other incorporated Imperial County cities, forms part of the larger populated area known as the Imperial Valley.
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