Researchers are exploring a new potential avenue for pancreatitis treatment: autophagy, a cellular recycling process.

Cerulein or alcohol impairs autophagy at multiple steps to promote pancreatitis. Cerulein or alcohol decreases pancreatic VMP1 to impair the closure of autophagosomes. Cerulein also decreases STX17 to ...

While better screening and improved treatments are leading to better outcomes for patients with breast cancer, 90% of breast cancer deaths are a result of metastasis, or the cancer growing and ...

Management outcomes of localized low-risk prostate cancer: A population-based study. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full text ...

Arginine pancreatitis was accompanied by a stress response with a large increase in the small heat shock protein HSP27, as well as HSP70, peaking at 24 hours and localised to acinar cells. There was a ...

Pancreatic ductal adenocarcinoma (PDAC) has long been considered to arise from pancreatic ducts on the basis of its morphology, the occurrence of dysplasia in putative preneoplastic ductal lesions, ...

Approximately 90% of the pancreas is made up of exocrine tissue comprising acinar cells, which secrete pancreatic enzymes, and ductal cells, which secrete bicarbonate rich fluid. About 1% of the ...

Steven was diagnosed with stage III locally advanced pancreatic acinar cell carcinoma – a very rare, highly aggressive form of pancreatic cancer – in 2012. He had surgery – not usual for someone with ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

Japanese industrial conglomerate Asahi Kasei Corp. has made an offer to acquire Swedish rare diseases specialist Calliditas Therapeutics AB for SEK11.8 billion (US$1.1 billion). The offer, at an 83% ...

The DNA damage response is a network of cellular pathways that sense, signal and repair DNA lesions. Surveillance proteins that monitor DNA integrity can activate cell cycle checkpoints and DNA ...

West China Center of Excellence for Pancreatitis, Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, China ...