Researchers are exploring a new potential avenue for pancreatitis treatment: autophagy, a cellular recycling process.
Cerulein or alcohol impairs autophagy at multiple steps to promote pancreatitis. Cerulein or alcohol decreases pancreatic VMP1 to impair the closure of autophagosomes. Cerulein also decreases STX17 to ...
Pancreas biopsies are graded according to the following histologic criteria: degree of inflammation, eosinophilia, acinar inflammation, ductal inflammation, endothelialitis, and necrotizing arteritis.
Approximately 90% of the pancreas is made up of exocrine tissue comprising acinar cells, which secrete pancreatic enzymes, and ductal cells, which secrete bicarbonate rich fluid. About 1% of the ...