The review discusses how metabolic cell death, distinct from traditional forms of regulated cell death like apoptosis, arises from imbalances in cellular metabolism due to nutrient and metal overload ...

Coagulation studies should indicate decreased fibrinogen and prothrombin, while ABG/VBG should show metabolic acidosis, respiratory alkalosis, and elevated lactate levels. ECG should show variety of ...

In a keynote presentation at ATS 2024, Hannah Wunsch, MD, MSc, of Weill Cornell Medicine, delved into how the history of ...

This review examines the mechanisms and therapeutic potential of various forms of metabolic cell death in cancer, including ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis.

A person with a pH imbalance may have high acid levels, called “acidosis,” or high bases, known as “alkalosis.” A pH imbalance is a serious concern and indicates an underlying health ...

21 Patients with very severe ulcerative colitis often have metabolic alkalosis. It has been shown that arterial blood pH rises progressively with the increased severity of the colitis and as the ...

The typical presentation of patients with Liddle syndrome includes early-onset severe hypertension, hypokalemia, metabolic alkalosis in the setting of low plasma renin and aldosterone, low rates ...

Seventy-three subjects had hypocarbia and respiratory alkalosis. Carbon dioxide retention (observed in 11 patients) occurred only at extreme degrees of obstruction. Age, history of asthma and ...

Clinical findings include dehydration, acidosis due to inadequate nutrition, alkalosis due to loss of hydrochloride and hypokalaemia. There are two degrees of severity: (i) grade 1, nausea and ...

9 Furthermore, overzealous and/or insufficiently monitored attempts to correct low serum bicarbonate levels could also result in the development of metabolic alkalosis and potentially the re ...

Purpose: The purpose of this study was to evaluate the effect of pre-exercise alkalosis, induced via ingestion of sodium bicarbonate, on changes to lactate/pH regulatory proteins and mitochondrial ...

Metabolic acidosis may be caused by kidney failure or severe diarrhea, while metabolic alkalosis may be caused by chronic vomiting or the use of steroids. In contrast, respiratory acidosis means ...