Human skin, hair and nails are all vulnerable to fungal infections. While these infections are usually not serious, they're ...

A new study suggests that adding common bone loss drugs to azoles can improve efficacy when treating fungal infections.

The first-line drugs for treatment of glucocorticoid-induced osteoporosis include bisphosphonates: alendronate and risedronate, while zoledronate or teriparatide should be considered as the second ...

The more potent zoledronate is an attractive alternative as it is administered less frequently. This study compares the clinical efficacy of intravenous pamidronate (1.5 mg/kg/day over 2 days, every 3 ...

Behavioral interventions, such as cognitive behavioral therapy (CBT) and physical activity, can help mitigate adverse effects of androgen-deprivation therapy (ADT), including fatigue, depressive ...

Bone metastases profoundly perturb normal bone remodeling. Biochemical markers of bone turnover have been shown to reflect these tumor-induced changes in bone remodeling and might therefore be ...

From Experimental Medicine, Imperial College London, Hammersmith Hospital, United Kingdom (M.R.W., H.-A.G., L.Z.); Excellence Cluster Cardio-Pulmonary System ...

The tumor microenvironment is closely linked to the initiation, promotion, and progression of solid tumors. Among its constitutions, immunologic cells emerge as critical players, facilitating immune ...

In the intricate landscape of immunology, the polarization of cellular immune response is a pivotal mechanism shaping the outcomes of inflammatory processes and cancer progression. This phenomenon, ...

From Experimental Medicine, Imperial College London, Hammersmith Hospital, United Kingdom (M.R.W., H.-A.G., L.Z.); Excellence Cluster Cardio-Pulmonary System ...