University of Pittsburgh researchers Dr. Farzad Esni, Ph.D., and Jing Hu, Ph.D., did an experiment in mice where they deleted ...

The experiment, the results of which were published May 3 in Nature Communications, used a focal adhesion kinase-inhibiting drug that is being studied in cancer treatment. Researchers found that the ...

Researchers show that a FAK-inhibiting drug, which has been studied in cancer treatment, converted acinar cells into acinar-derived insulin-producing (ADIP) cells and helped regulate blood glucose in ...

A drug used for the treatment of pancreatic cancer can be repurposed to replace insulin therapy among people with diabetes, ...

Pancreatic acinar cells form a heterogeneous population of new cell types in response to injury with the potential to limit or drive disease. Acinar-derived clones labeled in red and green.

Fluorescent imaging of acinar-derived insulin-producing cells (red and green) embedded among regular beta cells (green) in mice treated with a low dose of streptozotocin followed by a FAK ...

Lyme disease is the most common disease transmitted by tick bites in Germany. Whether a particular genetic predisposition plays a role in the development of the disease and which immunological ...

The presence of acinar inflammation is essential for the histological diagnosis of adult NASH. Portal inflammation is increasingly recognized as an important feature of NASH, probably mediated by ...

In this study, we show that inhibition of focal adhesion kinase activity results in transdifferentiation of a subset of peri-islet acinar cells into functional insulin producing β-like cells.

These cells are called acinar adenocarcinomas. Cancer occurs when abnormal cells begin to divide and grow uncontrollably. According to the charity, the majority of cases of prostate cancer grow ...