30% (136/453) patients with persisting respiratory acidosis did not receive NIV while 11% (15/131) of acidotic admissions had a pure metabolic acidosis and did. Hospital mortality was 25% (270/1077) ...

AMMONIUM chloride has been widely used as a therapeutic agent ever since its introduction by Keith, Barrier and Whelan 1 in 1925. Given intermittently for a few days at a time, it has a slight ...

Congenital lactic acidosis refers to a group of inborn errors of metabolism characterized in the neonatal period by metabolic acidosis associated with an overwhelming accumulation of lactate.

Diagnosis. Lactic acidosis associated with prolonged exposure to linezolid. Management. Discontinuation of linezolid. Lactic acidosis is a common disorder associated with disturbed acid–base ...

Respiratory acidosis (primary hypercapnia) is when blood becomes too acidic because your lungs are unable to remove enough carbon dioxide from your body. This potentially life-threatening condition ...

A normal blood pH is considered to be 7.35–7.45. However, even at a normal blood pH metabolic acidosis can occur. In fact, once the blood pH falls below 7.4, there is usually acid retention in the ...

Conclusions—On the basis of these findings, we conclude that acidosis-induced coronary arteriolar dilation is mediated by the opening of smooth muscle K ATP channels through the activation of ...

A recent study by University Medicine Halle shows how sepsis can lead to dysfunction of vascular smooth muscle cells. The ...

Lactic acidosis is a health condition characterized by elevated lactate levels in the body. These high lactate levels may result from increased cell production, decreased clearance (mainly within the ...

Am J Health Syst Pharm. 2008;65(15):1430-1434. Kathryn D. Mathews, PharmD, is Cardiology Clinical Pharmacist, Intermountain Medical Center, Murray, UT; at the time of writing, she was Cardiology ...

Further investigations revealed urinary acidification defect with hypercalciuria pointing towards distal renal tubular acidosis. Both patients were started on copper chelation therapy and showed ...

Objective: To compare the prognostic abilities of lactic acidosis and hyperlactatemia and determine the influence of metabolic acidosis when attempting to predict the outcome of septic patients using ...