A new paradigm The new structures, with resolutions around 3.5 Ångstrom, show that formins encircle actin like an asymmetric ring: One half of the ring is stably bound, while the other half is ...

Cell migration begins with protrusion of the cell membrane, followed by the formation of new adhesions at the cell front that link the actin cytoskeleton to the substratum, generation of traction ...

The new structures, with resolutions around 3.5 Ångstrom, show that formins encircle actin like an asymmetric ring: One half of the ring is stably bound, while the other half is loosely ...

Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. The proteins of the formin ...

utas.edu.au Background: The use of reverse transcription-polymerase chain reaction (RT-PCR) to measure mRNA levels has led to the common use of β-actin and GAPDH housekeeping genes as denominators for ...

No studies to date have reported the complete characterization of the regulatory regions required to drive in vivo expression of SM α-actin during development and maturation. Wang et al 34 recently ...