University of Pittsburgh researchers Dr. Farzad Esni, Ph.D., and Jing Hu, Ph.D., did an experiment in mice where they deleted ...

The experiment, the results of which were published May 3 in Nature Communications, used a focal adhesion kinase-inhibiting drug that is being studied in cancer treatment. Researchers found that the ...

Researchers show that a FAK-inhibiting drug, which has been studied in cancer treatment, converted acinar cells into acinar-derived insulin-producing (ADIP) cells and helped regulate blood glucose in ...

Fluorescent imaging of acinar-derived insulin-producing cells (red and green) embedded among regular beta cells (green) in mice treated with a low dose of streptozotocin followed by a FAK ...

Without enough insulin, diabetics could be at risk for hyperglycemia. A drug used for the treatment of pancreatic cancer can be repurposed to replace ...

The presence of acinar inflammation is essential for the histological diagnosis of adult NASH. Portal inflammation is increasingly recognized as an important feature of NASH, probably mediated by ...

Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of ...

These tumors form in the glandular cells that make prostate fluid. There are two types of adenocarcinoma: acinar adenocarcinoma and ductal adenocarcinoma. Acinar adenocarcinoma develops in the ...

For 30 years, doctors have known that maintaining near-normal blood sugar has huge benefits for people with type 1 diabetes. A 1993 clinical trial found that participants who were taught methods ...

They studied the PAE by light and electron microscopy, histochemistry, and by construction of a three-dimensional model of a dilated acinar ductal system from serial semi-thick Epon sections.

In this study, we show that inhibition of focal adhesion kinase activity results in transdifferentiation of a subset of peri-islet acinar cells into functional insulin producing β-like cells.

These cells are called acinar adenocarcinomas. Cancer occurs when abnormal cells begin to divide and grow uncontrollably. According to the charity, the majority of cases of prostate cancer grow ...