Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

New research is revealing potential impacts on the hormones of sea turtles affected by the Deepwater Horizon oil spill in the Gulf of Mexico.The 2010 ...

It is unclear whether these beneficial effects are due solely to aldosterone blockade, as MR has a similar affinity for cortisol. We examined the relationships between plasma and urinary steroid ...

Researchers from Tokyo Medical and Dental University (TMDU) find that the cells that make up aldosterone-producing adenomas become more transcriptionally active and express higher levels of genes ...

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Blockade of the renin–angiotensin system has beneficial effects in patients with diabetic nephropathy; however, this treatment can induce aldosterone breakthrough and thus become ineffective.

Their main job is to produce important hormones, like cortisol, aldosterone, adrenaline (epinephrine) and noradrenaline (norepinephrine), as well as sex hormones. Related: 6 Fast Ways to Lower ...

Boehringer Ingelheim says it is on track to launch 25 new treatments in its human pharma division onto the market between now ...

“There are four main classes of therapy we recommend,” he says. These include beta blockers, aldosterone blockers, a medication called sacubitril/valsartan that widens blood vessels, and what’s known ...

It clinical-stage product candidate is lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor for the treatment of cardiorenal conditions affected by ...

By binding to the angiotensin receptor 1, valsartan helps lower blood pressure and aldosterone levels, thereby preventing the ...