The functional autocrine loop constituted by coexpression of the KIT receptor tyrosine kinase (TK) and its ligand stem cell factor was first reported in small-cell lung cancer (SCLC) tumors and ...

Chemokines display autocrine, paracrine and hormonal roles in promoting cellular transformation, tumor growth, invasion and homing and metastasis to distant preferential organs (Fig. 1).

Angela is passionate about teaching chemistry and conducting undergraduate research. She is a member of the American Society for Biochemistry and Molecular Biology and the Hemingway Society. Bolduc, K ...

Raf activation induces synthesis and secretion of EGF-like growth factors, thereby providing an autocrine proliferative loop. Changes in the transcriptional regulation of several genes that are ...