In 1902, shortly after the rediscovery of Gregor Mendel's work by William Bateson 1 and just a few years after the word biochemistry was first coined, Archibald Garrod 2, a practicing physician at ...
HGO deficiency causes the metabolic disease alkaptonuria (AKU) 2. Homogentisate accumulation causes insoluble ochronotic pigments to deposit in connective tissues, resulting in degenerative ...