In 1902, shortly after the rediscovery of Gregor Mendel's work by William Bateson 1 and just a few years after the word biochemistry was first coined, Archibald Garrod 2, a practicing physician at ...
After observing how alkaptonuria was passed on in families, Garrod proposed that this disease and similar ‘inborn errors of metabolism’ were caused by a defective gene producing a ...