Many states test for arginase and citrin deficiencies. A handful also test for OTC and CPS1 deficiencies. Long-term treatment can manage UCD symptoms. Your child will need frequent blood tests ...

Its product, Pegzilarginase, is in a Phase 3 pivotal trial for the treatment of Arginase 1 Deficiency. The company was founded by George Georgiou and David G. Lowe on December 16, 2013 and is ...

This inherited condition is caused by a deficiency of the arginase enzyme, leading to arginine accumulation in the bloodstream. Any accumulation of arginine can cause brain damage, epilepsy ...

Both small molecules like flavonoids and biologics (arginase enzymes) have been developed at PolyU by the State Key Laboratory of Chemical Biology and Drug Discovery and the Department of Applied ...

Other programs include IO112, a product candidate containing a single arginase 1 (ARG-1)-derived peptide and designed to engage and activate ARG-1-specific human T cells (Fig. 2). IO Biotech has ...

ALA = Amoebic liver abscess; Eh = Entamoeba histolytica; EhCP = E. histolytica cysteine proteinase; Ehserp = E. histolytica serine proteinase; EhSTIRP = Serine threonine isoleucine-rich protein ...

Whereby we observed that MCTR3 protected both joint and cartilage, upregulating the expression of joint reparative pathways including Arginase 1 and polyamines and downregulating the expression of ...

Arimoclomol for treating Niemann-Pick disease Type C [ID1312] Highly specialised technology TBC Fosdenopterin for treating molybdenum cofactor deficiency type A [ID6264] Highly specialised technology ...