M.A., B.G.N.), University of Copenhagen, Copenhagen, Denmark. Background— We tested the hypothesis that the hereditary hemochromatosis genotypes C282Y/C282Y, C282Y/H63D, or C282Y/wild-type are risk ...

Genomic screening to identify hemochromatosis-;a disorder that causes iron levels in the body to rise to dangerous levels-;encourages people with the condition to seek treatment and ongoing ...

P.T., J.T.S.); and the Department of Medicine, University of Helsinki, Helsinki, Finland (K.K., T.H.). Background—Homozygosity for a relatively common Cys282Tyr mutation of the human ...

Hemochromatosis is a disease involving a buildup of iron in the blood, too much of which can be toxic and lead to serious health complications. The disease is usually caused by an inherited ...

Purpose: The recent discovery of the HFE gene and its association with hereditary hemochromatosis has renewed the attention directed to iron-overload diseases. Population screening for hereditary ...

Although hemochromatosis is often classified as a liver disease, it should be emphasized that it is a systemic genetic disease with multisystem involvement. The liver has, however, been central ...

Hemochromatosis is an autosomal recessive condition and the HFE gene is localized to chromosome 6. The typical hemochromatosis patient carries 2 copies of the C282Y mutation of the HFE gene (C282Y ...