The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes ...

Liver disease, hereditary, passed through families. Factors like viral infections, alcohol, obesity lead to liver damage, ...

Father, son among 3 killed in strike on Rafah home, while ‘continuous’ Israeli shelling hits north Gaza neighbourhoods.

P.T., J.T.S.); and the Department of Medicine, University of Helsinki, Helsinki, Finland (K.K., T.H.). Background—Homozygosity for a relatively common Cys282Tyr mutation of the human ...

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Four fifths of 49 patients with chronic, severe anemia from birth have manifested, usually during the second decade, signs of hemochromatosis with cardiac involvement. Nineteen patients had 33 attacks ...

Hemochromatosis is a disease involving a buildup of iron in the blood, too much of which can be toxic and lead to serious health complications. The disease is usually caused by an inherited ...

Purpose: The recent discovery of the HFE gene and its association with hereditary hemochromatosis has renewed the attention directed to iron-overload diseases. Population screening for hereditary ...

Cirrhosis is a condition that causes extreme scarring and damage to the liver. Scarring replaces healthy tissue in your liver with hard scar tissue, making it difficult for your liver to function ...

Although hemochromatosis is often classified as a liver disease, it should be emphasized that it is a systemic genetic disease with multisystem involvement. The liver has, however, been central ...

Hemochromatosis is an autosomal recessive condition and the HFE gene is localized to chromosome 6. The typical hemochromatosis patient carries 2 copies of the C282Y mutation of the HFE gene (C282Y ...