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- Cavernous transformation of the portal vein is a condition where the portal vein is blocked by a blood clot and replaced by many small veins12. This happens when portal vein thrombosis (PVT), which is the formation of a blood clot in the portal vein, does not resolve over time2. The new veins form collaterals that bypass the obstruction and bring blood to the liver2.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Cavernous transformation of the portal vein is a sequela of portal vein thrombosis and is the replacement of the normal single channel portal vein with numerous tortuous venous channels.radiopaedia.org/articles/cavernous-transformation-…Chronic PVT develops in patients with acute PVT that does not resolve (with or without treatment). Patients with chronic PVT develop collateral blood vessels that bring blood in a hepatopetal manner around the area of obstruction, known as cavernous transformation of the portal vein or portal cavernoma.www.uptodate.com/contents/chronic-portal-vein-thr…
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